Research Peptide Quality Guides

A practical guide to reading a research peptide COA: lot numbers, HPLC purity, mass spectrometry identity, net peptide content, endotoxin and sterility results, and the red flags to watch for.

Understand how reversed-phase HPLC measures research peptide purity, how to read a chromatogram, and why purity percentage alone does not tell the whole story.

What bacterial endotoxins are, how the Limulus Amebocyte Lysate (LAL) assay detects them, how results are reported in EU/mL, and why endotoxin matters in cell-based research.

Best practices for storing and handling lyophilized peptides in the laboratory: temperature, moisture, light, reconstitution, aliquoting and freeze-thaw cycles.

An explanation of the Research Use Only (RUO) designation: what it covers, what it does not, and the responsibilities of laboratories that purchase RUO materials.

Why incoming research peptide lots should be quarantined until testing is complete, what a release decision involves, and what happens to lots that fail.